Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 153
interventional 82
Observational 56
Registry 15

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 21
Other 19
Device 9
Drug|placebo 9
Diagnostic Test 5
Behavioral 4
Drug|Other 3
Behavioral|Drug 2
Device|Drug 2
Behavioral|Device|Drug 1
Behavioral|Other 1
Biological|Device 1
Dietary Supplement 1
Dietary Supplement|placebo 1
Drug|Procedure|Radiation 1
placebo|Procedure 1
Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 14
Egypt 9
NA 6
France 5
United Kingdom 5
Brazil 4
Canada 4
India 3
Israel 3
Pakistan 3
Panama 3
Turkey 3
Ireland 2
Malawi 2
Australia 1
Bangladesh 1
Belgium 1
China|Hong Kong|Indonesia|Japan|Malaysia|Philippines|Singapore|Taiwan|Thailand|Vietnam 1
Congo|Guatemala|Kenya|Pakistan|Zambia 1
Denmark 1
France|Martinique 1
Ghana 1
India|Mozambique|Nigeria|Pakistan 1
Indonesia 1
Italy 1
Netherlands 1
Norway 1
Spain 1
Tanzania 1
Thailand 1

Sites per Study

Site_count Study_Count
1 59
2 9
3 3
4 2
5 2
7 2
8 2
13 1
17 2

Phase

Phase Study_Count
N/A 49
Phase 3 11
Phase 2 7
Phase 4 7
Phase 2/Phase 3 5
Phase 1/Phase 2 2
Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 11
2 51
3 10
4 2
NA 8

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 4.000 116 34.00 50.00 30 2.0 74.0000
1st Qu. 89.000 116 70.25 58.25 114 22.5 92.0000
Median 180.000 116 106.50 115.00 116 150.0 222.0000
Mean 6778.143 116 106.50 133.50 152 331.1 357.1429
3rd Qu. 2200.000 116 142.75 180.00 220 609.5 457.0000
Max. 87500.000 116 179.00 280.00 280 1000.0 1106.0000

Trial Group Type

group_type Group_Count
Experimental 60
Active Comparator 36
No Intervention 31
Placebo Comparator 13
Other 10
NA 8
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Parallel Assignment 55
Single Group Assignment 17
Crossover Assignment 6
NA 3
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Prevention 30
Treatment 24
Diagnostic 10
Health Services Research 6
Device Feasibility 3
Other 3
Supportive Care 3
Educational/Counseling/Training 1
Screening 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
France 11
Egypt 9
United States 9
NA 8
Canada 2
Netherlands 2
United Kingdom 2
Australia|Canada|Jamaica|United Kingdom 1
Brazil 1
China 1
China|Hong Kong|India|Japan|Singapore|Taiwan|Thailand 1
India 1
Kenya 1
Malaysia 1
Nigeria 1
South Africa 1
Taiwan 1
Thailand 1
Turkey 1
United States|South Africa 1

Sites per Study

Site_count Study_Count
1 46
2 3
4 2
7 1
14 1
15 1
24 1
59 1

Enrollment Metrics

Measure Observational
Min 22.000
1st Qu 67.750
Median 143.000
Mean 1381.115
3rd Qu 500.000
Max 32000.000

Observation Model

observational_model Study_Count
Cohort 27
Case-Control 9
Case Control 7
Case-Only 5
NA 4
Case Control, Natural History 1
Defined Population 1
Ecologic or Community 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 40
Retrospective 6
Cross-Sectional 4
NA 3
Cross-Sectional, Prospective 1
Cross-Sectional, Retrospective/Prospective 1
Other 1

Registries

Studies by Country

Country Study_Count
Egypt 3
Denmark 2
NA 2
Belgium 1
Bolivia|Colombia|Guatemala|Honduras|Panama|Peru 1
Italy 1
Korea, Republic of 1
Mexico 1
Sierra Leone 1
Sweden 1
United States 1

Sites per Study

Site_count Study_Count
1 11
2 1
3 1
5 1
8 1

Enrollment Metrics

Measure Registries
Min 20.00
1st Qu 55.50
Median 100.00
Mean 19558.13
3rd Qu 1288.50
Max 222776.00

Registry Model

observational_model Study_Count
Case-Control 8
Cohort 6
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 11
Cross-Sectional 2
Other 2

Follow-up

target_duration Study_Count
3 Months 3
2 Days 2
9 Months 2
1 Day 1
1 Year 1
10 Years 1
11 Months 1
20 Years 1
3 Weeks 1
33 Years 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03356106 Screening and Treatment of Obstructive Sleep Apnea in High-risk Pregnancy https://ClinicalTrials.gov/show/NCT03356106 Recruiting Ramathibodi Hospital 2019-11-30
NCT03342014 First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler Angiography https://ClinicalTrials.gov/show/NCT03342014 Recruiting Central Hospital, Nancy, France 2021-11-30
NCT03334149 Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension https://ClinicalTrials.gov/show/NCT03334149 Active, not recruiting University of Oxford 2020-06-30
NCT03323762 Effect of RIC on BP and Inflammatory Response in Women With Pre-eclampsia https://ClinicalTrials.gov/show/NCT03323762 Recruiting University of Aarhus 2021-12-01
NCT03298802 Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide https://ClinicalTrials.gov/show/NCT03298802 Recruiting The University of Texas Medical Branch, Galveston 2021-04-30
NCT03252496 Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery https://ClinicalTrials.gov/show/NCT03252496 Recruiting Mansoura University 2020-08-31
NCT03232762 Effects of Diet on Pregnancy Outcome and Child Obesity https://ClinicalTrials.gov/show/NCT03232762 Completed NYU Langone Health 2019-08-22
NCT03164304 Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia https://ClinicalTrials.gov/show/NCT03164304 Completed Assiut University 2020-01-30
NCT03101150 Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia https://ClinicalTrials.gov/show/NCT03101150 Completed King Fahad Medical City 2014-10-31
NCT03028194 Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia https://ClinicalTrials.gov/show/NCT03028194 Completed Saint Thomas Hospital, Panama 2016-10-31
NCT03018132 Preeclampsia Research on Vitamin D, Inflammation, & Depression https://ClinicalTrials.gov/show/NCT03018132 Recruiting Cedars-Sinai Medical Center 2019-04-01
NCT02891174 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy https://ClinicalTrials.gov/show/NCT02891174 Completed University of Michigan 2018-03-31
NCT02881073 Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia https://ClinicalTrials.gov/show/NCT02881073 Completed Irish Centre for Fetal and Neonatal Translational Research 2019-04-26
NCT02801695 Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for Pre-eclampsia (CITRUPE) https://ClinicalTrials.gov/show/NCT02801695 Recruiting Nantes University Hospital 2021-04-20
NCT02797353 Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan https://ClinicalTrials.gov/show/NCT02797353 Completed Aga Khan University 2016-06-30
NCT02765906 Comparing Different Methods of Patient Education on Preeclampsia https://ClinicalTrials.gov/show/NCT02765906 Completed Geisinger Clinic 2017-07-30
NCT03391609 Peri-operative Dexmedetomidine Infusion in Pre-eclamptic Patients https://ClinicalTrials.gov/show/NCT03391609 Completed Assiut University 2018-11-01
NCT02531490 Early Vascular Adjustments During Hypertensive Pregnancy https://ClinicalTrials.gov/show/NCT02531490 Recruiting Maastricht University Medical Center 2021-02-28
NCT02333240 Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study https://ClinicalTrials.gov/show/NCT02333240 Completed University of Oxford 2016-11-30
NCT02319174 Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Pregnant Women https://ClinicalTrials.gov/show/NCT02319174 Completed William Marsh Rice University 2015-06-30
NCT02301780 Combined Multi-marker Screening and Treatment With Aspirin for Pre-eclampsia Prevention https://ClinicalTrials.gov/show/NCT02301780 Completed Rabin Medical Center 2016-10-31
NCT02296931 Assessment of a Syringe Pump to Pre-eclamptic Women in a Low-resource Hospital https://ClinicalTrials.gov/show/NCT02296931 Completed William Marsh Rice University 2015-10-31
NCT02267577 Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Adult Volunteers https://ClinicalTrials.gov/show/NCT02267577 Completed William Marsh Rice University 2015-10-31
NCT02258256 Pilot Assessment of an Auto Blood Pressure Monitor https://ClinicalTrials.gov/show/NCT02258256 Completed William Marsh Rice University 2017-10-01
NCT02218931 ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes https://ClinicalTrials.gov/show/NCT02218931 Completed Queen Mary University of London 2016-11-30
NCT02214186 Restrictive Fluid Therapy in Severe Preeclampsia https://ClinicalTrials.gov/show/NCT02214186 Completed University of Sao Paulo General Hospital 2015-03-31
NCT02086994 Prevention of Postpartum Hemorrhage in Patients With Severe Preeclampsia Using Carbetocin Versus Misoprostol https://ClinicalTrials.gov/show/NCT02086994 Completed Benha University 2015-08-31
NCT01278459 Can Atorvastatin Improve Vascular Function in Women With a History of Preeclampsia? https://ClinicalTrials.gov/show/NCT01278459 Completed University of Oxford 2012-04-30
NCT02050529 Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. https://ClinicalTrials.gov/show/NCT02050529 Completed Dow University of Health Sciences 2014-09-30
NCT01990625 A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings https://ClinicalTrials.gov/show/NCT01990625 Completed NICHD Global Network for Women’s and Children’s Health 2016-08-31
NCT01988298 Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia https://ClinicalTrials.gov/show/NCT01988298 Completed Complejo Hospitalario Dr. Arnulfo Arias Madrid 2015-02-28
NCT01972659 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients https://ClinicalTrials.gov/show/NCT01972659 Completed Kocaeli University 2013-12-31
NCT01911494 Community Level Interventions for Pre-eclampsia https://ClinicalTrials.gov/show/NCT01911494 Completed University of British Columbia 2018-05-31
NCT01907620 Circulating Oxidative Stress and Gestational Hypertension. Study of the Evolution of Free-radical Markers of Oxidative Stress From Before to After Childbirth in Two Groups of Women: Normal Pregnancy and Pre-eclampsia. https://ClinicalTrials.gov/show/NCT01907620 Completed Centre Hospitalier Universitaire Dijon 2011-11-30
NCT03650790 C1q/TNF-related Protein 9 (CTRP 9) Level in Preeclamptic Obese and Non-obese Pregnancies https://ClinicalTrials.gov/show/NCT03650790 Completed Diyarbakir Women’s and Children’s Diseases Hospital 2019-01-01
NCT01865656 A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka https://ClinicalTrials.gov/show/NCT01865656 Completed Harvard School of Public Health 2014-10-31
NCT01846156 New Magnesium Sulphate Protocol for Pre-eclampsia https://ClinicalTrials.gov/show/NCT01846156 Completed Cairo University 2014-04-30
NCT01801410 Induction With Foley OR Misoprostol (INFORM) Study https://ClinicalTrials.gov/show/NCT01801410 Completed University of Liverpool 2015-06-30
NCT01766089 Dexmedetomidine vs. Remifentanil for Pre-eclampsia During Caesarean Delivery https://ClinicalTrials.gov/show/NCT01766089 Completed Mansoura University 2016-12-31
NCT01751945 Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project https://ClinicalTrials.gov/show/NCT01751945 Completed Aga Khan University 2013-12-31
NCT01729468 Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers https://ClinicalTrials.gov/show/NCT01729468 Completed University Hospital, Tours 2016-10-25
NCT01606774 A Modernized Approach to Prenatal Care in Low Risk Women https://ClinicalTrials.gov/show/NCT01606774 Completed Massachusetts General Hospital 2014-04-30
NCT01480544 Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE) https://ClinicalTrials.gov/show/NCT01480544 Completed Duke University 2014-12-31
NCT01395342 Assessment of Physical Exercise Using Stationary Bicycle for Pregnant Women With Risk for Preeclampsia Development https://ClinicalTrials.gov/show/NCT01395342 Completed University of Campinas, Brazil 2011-11-30
NCT01352234 Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia https://ClinicalTrials.gov/show/NCT01352234 Completed CHU de Quebec-Universite Laval 2014-12-31
NCT01351428 Goal-Directed Therapy in Pregnant Women at High Risk of Developing Preeclampsia https://ClinicalTrials.gov/show/NCT01351428 Completed Samuel Lunenfeld Research Institute, Mount Sinai Hospital 2012-11-30
NCT04204018 Measuring Practice Pattern Changes and Clinical Utility of a Novel Test for Preeclampsia https://ClinicalTrials.gov/show/NCT04204018 Completed Qure Healthcare, LLC 2019-12-23
NCT04092829 Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer https://ClinicalTrials.gov/show/NCT04092829 Recruiting Instituto Valenciano de Infertilidad, IVI VALENCIA 2020-08-31
NCT04004897 Optic Nerve Sheath Diameter in Preeclampsia https://ClinicalTrials.gov/show/NCT04004897 Completed Kanuni Sultan Suleyman Training and Research Hospital 2019-11-20
NCT03993145 Lifestyle Intervention for Women With Recent Pre-eclampsia or Gestational Diabetes Mellitus (‘Mom’s Healthy Heart’) https://ClinicalTrials.gov/show/NCT03993145 Enrolling by invitation Norwegian University of Science and Technology 2022-03-31
NCT03978429 An mHealth Strategy to Reduce Pre-Eclampsia and Infant Death in Tanzania https://ClinicalTrials.gov/show/NCT03978429 Recruiting Queen’s University 2020-04-01
NCT03968952 SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in Rural India. https://ClinicalTrials.gov/show/NCT03968952 Recruiting University of Oxford 2020-12-01
NCT03961360 Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida https://ClinicalTrials.gov/show/NCT03961360 Recruiting The University of Texas Health Science Center, Houston 2020-05-01
NCT03941886 Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST) https://ClinicalTrials.gov/show/NCT03941886 Recruiting Chinese University of Hong Kong 2022-03-31
NCT03893630 Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia https://ClinicalTrials.gov/show/NCT03893630 Recruiting University of Kentucky 2021-06-30
NCT03858595 Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy https://ClinicalTrials.gov/show/NCT03858595 Recruiting International Centre for Diarrhoeal Disease Research, Bangladesh 2020-10-31
NCT03750695 Acute Exercise Effects in Obese Pregnancy https://ClinicalTrials.gov/show/NCT03750695 Completed Duke University 2020-03-31
NCT03749044 ASA Patterns for Prevention of Preeclampsia in SLE Pregnancies https://ClinicalTrials.gov/show/NCT03749044 Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre 2023-10-30
NCT03724786 Management of Suspected Preeclampsia Based on 6-hour Versus 24-hour Urine Protein Collection https://ClinicalTrials.gov/show/NCT03724786 Enrolling by invitation Wolfson Medical Center 2020-07-31
NCT03717701 Metformin and Esomeprazole in Treatment of Early Onset Preeclampsia https://ClinicalTrials.gov/show/NCT03717701 Recruiting Aswan University Hospital 2020-11-30
NCT03717740 Esomeprazole for the Prevention of Preeclampsia https://ClinicalTrials.gov/show/NCT03717740 Recruiting Aswan University Hospital 2021-11-30
NCT03648970 Indonesia Pravastatin to Prevent Preeclampsia Study https://ClinicalTrials.gov/show/NCT03648970 Recruiting Universitas Airlangga 2020-03-01
NCT03630276 Evaluation of Neutrophil/Lymphocyte Ratio ,Platelet/Lymphocyte Ratio and CRP as Markers of Severity of Pre-eclampsia https://ClinicalTrials.gov/show/NCT03630276 Recruiting Ain Shams University 2018-08-10
NCT03509805 Sleep Apnea Syndrome in Obese Women During Pregnancy https://ClinicalTrials.gov/show/NCT03509805 Completed University Hospital, Lille 2017-03-14
NCT03509272 LimPrOn: Limburg Pre-eclampsia Investigation https://ClinicalTrials.gov/show/NCT03509272 Recruiting Hasselt University 2030-12-31
NCT03466333 Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsia https://ClinicalTrials.gov/show/NCT03466333 Recruiting Manchester University NHS Foundation Trust 2020-10-31
NCT01229189 Evaluation of the Effectiveness of Vitamin D Supplementation to Pregnant Women and Their Infants in Pakistan. https://ClinicalTrials.gov/show/NCT01229189 Completed Aga Khan University 2011-08-31
NCT01140971 Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor https://ClinicalTrials.gov/show/NCT01140971 Completed Municipal Hospital Vila Nova Cachoeirinha 2008-03-31
NCT03674606 Trial of Early Screening Test for Pre-eclampsia and Growth Restriction https://ClinicalTrials.gov/show/NCT03674606 Completed University College Dublin 2016-04-13
NCT00809666 Measuring Blood Pressure in Pregnancy Using Mercury and Automated Device https://ClinicalTrials.gov/show/NCT00809666 Completed St George Hospital, Australia 2006-09-30
NCT02317146 Magnesium Sulfate in Pregnancy and Postpartum https://ClinicalTrials.gov/show/NCT02317146 Completed Complejo Hospitalario Dr. Arnulfo Arias Madrid 2016-12-31
NCT02468310 Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana https://ClinicalTrials.gov/show/NCT02468310 Completed Julius Global Health 2017-02-09
NCT00485784 Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications https://ClinicalTrials.gov/show/NCT00485784 Completed Assistance Publique Hopitaux De Marseille 2012-07-31
NCT00303173 The Relaxation and Blood Pressure in Pregnancy (REBIP) Study https://ClinicalTrials.gov/show/NCT00303173 Completed University of Toronto 2006-12-31
NCT00275158 Glomerular Injury of Preeclampsia https://ClinicalTrials.gov/show/NCT00275158 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NA
NCT00197340 Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction https://ClinicalTrials.gov/show/NCT00197340 Completed Hadassah Medical Organization 2006-12-31
NCT00158743 Efficacy Study of Digibind for Treatment of Severe Preeclampsia https://ClinicalTrials.gov/show/NCT00158743 Completed BTG International Inc. 2007-12-31
NCT00157521 L-Arginine in Pre-Eclampsia https://ClinicalTrials.gov/show/NCT00157521 Completed Mario Negri Institute for Pharmacological Research NA
NCT00097110 RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil https://ClinicalTrials.gov/show/NCT00097110 Completed NICHD Global Network for Women’s and Children’s Health NA
NCT00000543 Oral Calcium in Pregnant Women With Hypertension https://ClinicalTrials.gov/show/NCT00000543 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000534 Calcium for Pre-Eclampsia Prevention (CPEP) https://ClinicalTrials.gov/show/NCT00000534 Completed Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) NA
NCT00004399 Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia https://ClinicalTrials.gov/show/NCT00004399 Completed FDA Office of Orphan Products Development NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04455204 Adipokines, Inflammation, Insulin Resistance and Endothelial Dysfunction in Preeclampsia https://ClinicalTrials.gov/show/NCT04455204 Completed Tanta University 2019-09-30
NCT03316430 Podocyturia as Predictive Factor for Pre-eclampsia https://ClinicalTrials.gov/show/NCT03316430 Recruiting Hospices Civils de Lyon 2022-01-14
NCT03316391 Association Between Pococyturia and Pre-eclampsia Severity https://ClinicalTrials.gov/show/NCT03316391 Recruiting Hospices Civils de Lyon 2025-03-22
NCT03269110 Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child) https://ClinicalTrials.gov/show/NCT03269110 Enrolling by invitation Ottawa Hospital Research Institute 2021-07-31
NCT03151070 Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design https://ClinicalTrials.gov/show/NCT03151070 Completed Hospital San Juan de Dios Guatemala 2017-03-15
NCT03127865 Evaluation of Electrical Velocimetry for Assessment of Extra-vascular Lung Water in Pre-eclamptic Patients https://ClinicalTrials.gov/show/NCT03127865 Completed Cairo University 2017-08-14
NCT03111576 Vascular Changes in Pre-Eclamptic Patients and Its Impact on Pregnancy Outcome. https://ClinicalTrials.gov/show/NCT03111576 Recruiting Beni-Suef University 2019-05-31
NCT02992145 Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia https://ClinicalTrials.gov/show/NCT02992145 Completed Ain Shams Maternity Hospital 2016-12-31
NCT02935556 Characterization and Epigenetics of Post-Partum Preeclampsia https://ClinicalTrials.gov/show/NCT02935556 Recruiting Duke University 2021-02-28
NCT02807324 Women Specific Cardiac Recovery After Preeclampsia https://ClinicalTrials.gov/show/NCT02807324 Recruiting Maastricht University Medical Center 2022-06-30
NCT02721771 Acid-Base and Point of Care Ultrasound in Severe Preeclampsia https://ClinicalTrials.gov/show/NCT02721771 Completed University of Cape Town 2016-10-31
NCT02677233 Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study https://ClinicalTrials.gov/show/NCT02677233 Completed Ain Shams Maternity Hospital 2015-12-31
NCT02665897 Pre-eclampsia and Biochemical Markers https://ClinicalTrials.gov/show/NCT02665897 Completed Assiut University 2016-12-31
NCT02357264 Thoracic Ultrasonography for Pulmonary Edema in Patients With Pre-Eclampsia https://ClinicalTrials.gov/show/NCT02357264 Completed Maimonides Medical Center 2017-01-31
NCT02347540 Heart Failure and Related Risk-factors After Preeclampsia https://ClinicalTrials.gov/show/NCT02347540 Recruiting Maastricht University Medical Center 2019-12-31
NCT02164370 Evaluation of Metabolic Acid-base Abnormalities in Pre-eclamptic Women Applying the Stewart-Fencl Approach https://ClinicalTrials.gov/show/NCT02164370 Completed University of Washington 2014-04-30
NCT01925508 Evaluation of a Physical Therapy Protocol on Quality of Life Musculoskeletal Pain and Anxiety in Women With Preeclampsia https://ClinicalTrials.gov/show/NCT01925508 Completed University of Sao Paulo 2013-08-31
NCT01736826 Free DNA and Nucleosome Concentrations in Pathological Pregnancies https://ClinicalTrials.gov/show/NCT01736826 Completed Centre Hospitalier Universitaire de NÄ«mes 2018-12-17
NCT01669525 Placental Growth and Adverse Pregnancy Outcomes https://ClinicalTrials.gov/show/NCT01669525 Completed University of Pennsylvania 2016-06-30
NCT01665456 Assessing Childbirth-related Complications at the Community Level in Kenya https://ClinicalTrials.gov/show/NCT01665456 Completed Kenyatta National Hospital 2013-11-30
NCT01348711 Early Placental Insufficiency Screening https://ClinicalTrials.gov/show/NCT01348711 Completed University Hospital, Tours 2011-02-28
NCT04389099 MRI Angiography of Physiological and Pathological Pregnancy Placentas Ex-vivo https://ClinicalTrials.gov/show/NCT04389099 Recruiting Central Hospital, Nancy, France 2021-11-17
NCT04374604 Placental Growth Factor as a Predictor of Adverse Pregnancy Outcomes in Preeclamptic Women https://ClinicalTrials.gov/show/NCT04374604 Completed Alex Ekwueme Federal University Teaching Hospital 2019-07-22
NCT04239352 Preeclamptic Patients and Pentraxin 3 & Lipoprotein-associated Phospholipase A2 https://ClinicalTrials.gov/show/NCT04239352 Completed Kanuni Sultan Suleyman Training and Research Hospital 2020-05-20
NCT04170660 Interest of sFlt1/PlGF Ratio at Obstetric Emergencies https://ClinicalTrials.gov/show/NCT04170660 Recruiting Centre Hospitalier Intercommunal Creteil 2020-05-31
NCT04160923 Incidence and Neonatal Outcome of Eclamptic Parturient in Tertiary Hospital. https://ClinicalTrials.gov/show/NCT04160923 Completed Siriraj Hospital 2019-04-30
NCT04126122 Maternal and Neonatal Outcome in Severe Preeclampsia https://ClinicalTrials.gov/show/NCT04126122 Recruiting Aljazeera Hospital 2020-01-10
NCT04037683 qMOLI- A Qualitative Assessment of Misoprostol or Oxytocin for Labour Induction https://ClinicalTrials.gov/show/NCT04037683 Active, not recruiting University of Liverpool 2021-09-30
NCT04021680 Clinical Effectiveness of First Trimester Pre-eclampsia Screening Program. https://ClinicalTrials.gov/show/NCT04021680 Recruiting Far Eastern Memorial Hospital 2025-06-20
NCT03981029 FACT Biomarker Subgroup Analysis https://ClinicalTrials.gov/show/NCT03981029 Completed Ottawa Hospital Research Institute 2016-07-31
NCT03928691 Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level https://ClinicalTrials.gov/show/NCT03928691 Recruiting Assiut University 2020-08-31
NCT03882099 Vitamin D Level and Its Relation to Pre-eclampsia and Eclampsia https://ClinicalTrials.gov/show/NCT03882099 Recruiting Cairo University 2019-09-17
NCT03815110 Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification https://ClinicalTrials.gov/show/NCT03815110 Recruiting Cedars-Sinai Medical Center 2020-12-31
NCT03806283 Angiotensin 2 Receptor (AT2R) in Endothelial Cells in Preeclampsia https://ClinicalTrials.gov/show/NCT03806283 Active, not recruiting University of Wisconsin, Madison 2021-07-01
NCT03767803 Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women https://ClinicalTrials.gov/show/NCT03767803 Active, not recruiting Progenity, Inc. 2020-12-31
NCT03665623 Prediction of Preeclampsia by Comprehensive Markers. https://ClinicalTrials.gov/show/NCT03665623 Recruiting Peking Union Medical College Hospital 2018-12-31
NCT03626233 Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection https://ClinicalTrials.gov/show/NCT03626233 Recruiting Centre Hospitalier Intercommunal Creteil 2023-08-31
NCT03605511 TTP and aHUS in Complicated Pregnancies https://ClinicalTrials.gov/show/NCT03605511 Recruiting University College, London 2020-03-14
NCT03562715 microRNAs Role in Pre-eclampsia Diagnosis https://ClinicalTrials.gov/show/NCT03562715 Completed Cairo University 2017-06-15
NCT03554681 Prediction of Preeclampsia (PE) at 11-13 Week https://ClinicalTrials.gov/show/NCT03554681 Completed Chinese University of Hong Kong 2018-12-31
NCT03515759 Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients. https://ClinicalTrials.gov/show/NCT03515759 Completed Cairo University 2019-01-15
NCT03455387 Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy. https://ClinicalTrials.gov/show/NCT03455387 Recruiting Centre Hospitalier Metropole Savoie 2020-03-10
NCT03412552 Risk Analysis of Intensive Care Mangement on Maternal and Fetal Outcome of Severe Preeclampsia and Eclampsia https://ClinicalTrials.gov/show/NCT03412552 Completed Cairo University 2017-10-01
NCT01261351 Study of Coagulation Activation Markers and Pre Eclampsia https://ClinicalTrials.gov/show/NCT01261351 Completed University Hospital, Lille 2014-06-30
NCT01248169 Impedance Cardiographic (ICG) Assessment of Pregnant Women With Severe Hypertension to Assess Impact of Standard Therapy https://ClinicalTrials.gov/show/NCT01248169 Completed University of Mississippi Medical Center 2013-07-31
NCT00930397 Observational Study in UTERO - Placental 3D Doppler Examination: Interest for Pre-eclampsia Screening During Pregnancy https://ClinicalTrials.gov/show/NCT00930397 Completed Assistance Publique - Hôpitaux de Paris 2011-11-30
NCT00826696 A Retrospective Review of the Seasonality of Pre-Eclampsia https://ClinicalTrials.gov/show/NCT00826696 Completed Oklahoma State University Center for Health Sciences 2009-04-30
NCT02578810 PIERS and BIS, sFIT:PIGF, Adrenomedullin https://ClinicalTrials.gov/show/NCT02578810 Recruiting Suez Canal University 2020-05-31
NCT02443259 Neurobehavioural Outcomes in Late Preterm Neonates https://ClinicalTrials.gov/show/NCT02443259 Completed Lady Hardinge Medical College 2015-10-31
NCT00533871 Study to Determine if Serum BNP Levels Are Elevated in Pregnant Women With Pre-Eclampsia https://ClinicalTrials.gov/show/NCT00533871 Completed Ohio State University NA
NCT00465634 Doppler and Biological Second Trimester Placental Insufficiency Screening https://ClinicalTrials.gov/show/NCT00465634 Completed University Hospital, Tours 2007-06-30
NCT00438542 HMW-Adiponectin is Raised in Newborns https://ClinicalTrials.gov/show/NCT00438542 Completed University of Oslo NA
NCT00005207 Renin and Prorenin in Pregnancy https://ClinicalTrials.gov/show/NCT00005207 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00175695 Disease Modification in Toxaemia of Pregnancy https://ClinicalTrials.gov/show/NCT00175695 Completed University of British Columbia 2010-10-31
NCT00005456 Hypertensive and Normal Pregnancy–Calcium Metabolism and Renin-Angiotensin - SCOR in Hypertension https://ClinicalTrials.gov/show/NCT00005456 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005400 Angiotensinogen Variants and Adverse Pregnancy Outcomes https://ClinicalTrials.gov/show/NCT00005400 Completed University of Utah NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03360240 Blood Pressure in Adolescents With PReclampsia and Eclampsia. https://ClinicalTrials.gov/show/NCT03360240 Completed Complejo Hospitalario Dr. Arnulfo Arias Madrid 2018-03-08
NCT03330301 D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life https://ClinicalTrials.gov/show/NCT03330301 Completed Bispebjerg Hospital 2016-09-30
NCT03246542 Promising Bimarker Prediction of Outcome of HELLP Syndrome. https://ClinicalTrials.gov/show/NCT03246542 Completed Ain Shams Maternity Hospital 2015-12-01
NCT03193554 Diagnostic Value of MicroRNA 210 In Preeclampsia https://ClinicalTrials.gov/show/NCT03193554 Recruiting Assiut University 2020-05-01
NCT03143647 Magnesium and Platelet Function Testing https://ClinicalTrials.gov/show/NCT03143647 Completed Ziekenhuis Oost-Limburg 2017-07-30
NCT02982265 Pre-eclampsia/Eclampsia in Italy Over the Years 2010-2016 https://ClinicalTrials.gov/show/NCT02982265 Completed Papa Giovanni XXIII Hospital 2020-01-31
NCT02350036 Placental Protein 13 Serum Endoglin and Uterine Doppler Indeces as Predictors of Pre-eclampsia https://ClinicalTrials.gov/show/NCT02350036 Completed Cairo University 2016-12-31
NCT02020174 The Preeclampsia Registry https://ClinicalTrials.gov/show/NCT02020174 Recruiting Preeclampsia Foundation 2030-05-31
NCT04367519 Optic Nerve Sheath Diameter for Volume Status Prediction in Severe Preeclampsia https://ClinicalTrials.gov/show/NCT04367519 Completed Zagazig University 2020-03-30
NCT04142268 Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic Women After Delivery https://ClinicalTrials.gov/show/NCT04142268 Completed Seoul National University Hospital 2016-10-31
NCT03949829 The CoPenHagen PREeClampsia and cardIOvascUlar diSease Trial https://ClinicalTrials.gov/show/NCT03949829 Enrolling by invitation Rigshospitalet, Denmark 2021-06-30
NCT03856307 Reliability of Simple Sonographic Findings Acquired With Hand-held Apparatuses to Inform Obstetric Diagnosis https://ClinicalTrials.gov/show/NCT03856307 Completed Doctors with Africa - CUAMM 2019-04-01
NCT03831490 Study for Improving Maternal, Pregnancy and Child Outcomes https://ClinicalTrials.gov/show/NCT03831490 Recruiting Uppsala University 2020-11-09
NCT03755843 PREDICTION OF FLUID RESPONSIVENESS WITH PASSIVE LEG RISING IN PREGNANT PATIENTS WITH SEVERE PREECLAMPSIA https://ClinicalTrials.gov/show/NCT03755843 Completed Grupo Mexicano para el Estudio de la Medicina Intensiva 2017-07-31
NCT03232359 Immature Platelet Fraction as a Promising Biomarker in Prediction Outcome of HELLP Syndrome https://ClinicalTrials.gov/show/NCT03232359 Completed Ain Shams Maternity Hospital 2015-12-01